Penarol claimed its 52nd Uruguayan top-flight title on Sunday with a 3-1 home victory over Fenix.
Eduardo Darias gave the host the lead in the opening minute before Guillermo Pereira gifted Penarol a second goal by inadvertently turning the ball into his own net.
Pereira made amends with a 28th-minute strike, but Leonardo Fernandez restored his side's two-goal lead with a stunning 30-yard free-kick from a difficult angle just after halftime.
The result at Estadio Campeon del Siglo meant Penarol finished Uruguay's Primera Division Clausura season with 38 points, two points ahead of second-placed Nacional.
"Everyone at this club played their part in this triumph," Penarol manager Diego Aguirre said after the match.
"I'm proud of this team because we enjoyed ourselves and made a lot of people happy. Knowing that gives us a great deal of satisfaction."
Sunday's final day of matches confirmed Uruguay's participants in next year's continental tournaments.
Penarol, Nacional, Boston River and Defensor Sporting qualified for the Copa Libertadores, while Cerro Largo, Danubio, Racing and Montevideo Wanderers clinched berths in the Copa Sudamericana.
Meanwhile, Deportivo Maldonado, Fenix and Rampla Juniors were relegated to Uruguayan football's second tier.